Who should not use bupropion?

Allergies to Ingredients. People who are allergic to any of the following should not take bupropion.

Bupropion

Aplenzin

Forfivo XL

Wellbutrin

Wellbutrin SR

Wellbutrin XL

Zyban

Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in the specific bupropion products they stock.

Seizure Disorder or Epilepsy. Bupropion should not be taken if you have seizures or epilepsy.

Eating Disorder. Do not take bupropion if you have or have had an eating disorder, such as anorexia or bulimia. 

Suddenly Stopping Certain Medicines or Alcohol. Tell your healthcare provider if you drink a lot of alcohol and have suddenly stopped. Also tell your healthcare provider if you suddenly stop taking a medicine called a benzodiazepine (such as clonazepam or diazepam), barbiturate (such as phenobarbital or butalbital), or a medicine used for seizures (such as carbamazepine or phenytoin). See the Interactions section for more details. 

Drug Interactions. Bupropion should not be taken while you are using certain other medicines. Before taking bupropion, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.

Do not take bupropion unless it has been prescribed to you by a healthcare provider. Take it as prescribed. Do not stop taking bupropion without talking to your healthcare provider.

Do not share bupropion with other people, even if they have the same condition as you. It may harm them.

Do not chew, cut, or crush bupropion. Ask your pharmacist or other healthcare provider if you are not sure how to take the bupropion product you are prescribed.

Bupropion can affect your alertness or coordination. Do not drive or do other activities that require alertness or coordination until you know how bupropion affects you.

Keep bupropion out of the reach of children.

Bupropion may cause false-positive results on certain urine drug screenings for amphetamines. Tell all of your healthcare providers about the medicines you take.

Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if bupropion is right for you.

In particular, make sure that you discuss any of the following.

Current and Past Health Conditions. Tell your healthcare provider if you have any of the following.

Alcohol. Tell your healthcare provider if you drink alcohol or have recently stopped drinking alcohol.

Misuse. Tell your healthcare provider if you misuse prescription medicines or street drugs. Misuse means taking a medicine in a way other than how it was prescribed.

Pregnancy. It is not known if or how bupropion could affect pregnancy or harm an unborn baby. Tell your healthcare provider if you are or plan to become pregnant. Your healthcare provider will advise you if you should take bupropion while you are pregnant or trying to get pregnant. If you become pregnant while taking bupropion, talk to your healthcare provider to see if you should sign up for the National Pregnancy Registry for Antidepressants by calling 866-961-2388 or at . This registry collects safety information about the use of antidepressant medicines during pregnancy. 

Breastfeeding. Bupropion passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should take bupropion while breastfeeding.